Benigne Prostatahyperplasie (BPH) – Mikronährstofftherapie
Menschen mit Prostatahyperplasie gehören zu einer Risikogruppe, die anfälliger für einen Mangel folgender Vitalstoffe* ist:
- Selen [1]
Prostatahyperplasie als Mangelsymptom kann ein auf eine unzureichende Versorgung folgender Vitalstoffe* hinweisen:
- Zink [2]
Im Rahmen der Mikronährstoffmedizin werden zur unterstützenden Therapie von Prostatahyperplasie folgende Vitalstoffe* eingesetzt:
- Vitamine: E [3], D [4]
- Carotinoide: Beta-Carotin [5], Lycopin [6, 7]
- Epigallokatechingallate [8]
- Genistein [9, 10]
- Beta-Sitosterin [3, 11, 12]
- Kürbiskernöl [13-16]
- Citrus-Flavonoid-Extrakt [17]
- Schwarztee-Extrakt [18]
- Grüntee-Extrakt [18]
- Pinienrinde [19]
- Sägepalmen-Extrakt [20-25]
- Afrikanischer Pflaumenbaum-Extrakt [26]
- Brennnessel-Extrakt ]19, 24, 27-30]
Detaillierte Informationen zu den einzelnen Mikronährstoffen finden Sie im DocMedicus Vitalstofflexikon.
Die obigen Vitalstoff-Empfehlungen (Mikronährstoffe) wurden mithilfe des DocMedicus Expertensystems erstellt. Sämtliche Aussagen des Expertensystems sind durch Literatur mit hohen Evidenzgraden belegt.
Für eine Therapieempfehlung wurden nur klinische Studien mit den höchsten Evidenzgraden (Grad 1a/1b und 2a/2b) verwendet, die aufgrund ihrer hohen Aussagekraft die Therapieempfehlung belegen.
Hinweis!
Diese Daten werden in gewissen Zeitabständen aktualisiert.
Das DocMedicus Expertensystem ist stets auf dem aktuellen Stand der Vitalstoff-Forschung. Lassen Sie sich deshalb Ihre persönliche Vitalstoff-Analyse* mithilfe des DocMedicus Expertensystems bei Ihrem Arzt erstellen.
*Makronährstoffe (Kohlenhydrate, Fette, Proteine (Eiweiße)) und Mikronährstoffe (Vitamine, Mineralstoffe, Spurenelemente) sowie weitere Stoffe mit ernährungsspezifischer und physiologischer Wirkung
Vitalstoff-Analyse für den Mann
Männergesundheit – Vitalstoff-Analyse
Literatur
- Zachara B A, Szewczyk-Golec K, Tyloch J, Wolski Z, Szylberg T, Stepien S, Kwiatkowski S, Bloch-Boguslawska E, Wasowicz W. Blood and tissue selenium concentrations and glutathione peroxidase activities in patients with prostate cancer and benign prostate hyperplasia. Neoplasma. 2005 Dez; 52, 3: 248-54.
- Sauer Ann Katrin, Vela Hector, Vela Guillermo, Stark Peter, Barrera-Juarez Eduardo, Grabrucker Andreas M. Zinc Deficiency in Men Over 50 and Its Implications in Prostate Disorders. Front Oncol. 2020 Jan; 10: 1293.
- Preuss H G, Marcusen C, Regan J, Klimberg I W, Welebir T A, Jones W A. Randomized trial of a combination of natural products (cernitin, saw palmetto, B-sitosterol, vitamin E) on symptoms of benign prostatic hyperplasia (BPH). Int Urol Nephrol. 2001 Jan; 33, 2: 217-25.
- Colli Enrico, Rigatti Patrizio, Montorsi Francesco, Artibani Walter, Petta Stefano, Mondaini Nicola, Scarpa Roberto, Usai Paolo, Olivieri Lorenza, Maggi Mario. BXL628, a novel vitamin D3 analog arrests prostate growth in patients with benign prostatic hyperplasia: a randomized clinical trial. Eur Urol. 2006 Jan; 49, 1: 82-6.
- Marks L S, Partin A W, Epstein J I, Tyler V E, Simon I, Macairan M L, Chan T L, Dorey F J, Garris J B, Veltri R W, Santos P B, Stonebrook K A, deKernion J B. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol. 2000 Mai; 163, 5: 1451-6.
- Schwarz Silke, Obermüller-Jevic Ute C, Hellmis Eva, Koch Winfried, Jacobi Günther, Biesalski Hans-Konrad. Lycopene inhibits disease progression in patients with benign prostate hyperplasia. J Nutr. 2008 Jan; 138, 1: 49-53
- Li Yi-Ze, Liang Wei-Ning, Zhang Guo-Wei, Weng Zhi-Qiang, Zhong Yong, Xu Song, Shang Xue-Jun. Efficacy and safety of lycopene in the treatment of benign prostatic hyperplasia with lower urinary tract symptoms. Zhonghua Nan Ke Xue. 2019 Nov; 25, 11: 1001-1004.
- Bettuzzi Saverio, Brausi Maurizio, Rizzi Federica, Castagnetti Giovanni, Peracchia Giancarlo, Corti Arnaldo. Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia: a preliminary report from a one-year proof-of-principle study. Cancer Res. 2006 Jan; 66, 2: 1234-40.
- Brössner Clemens, Petritsch Karin, Fink Klaus, Auprich Marco, Madersbacher Stephan, Adlercreutz Herman, Rehak Peter, Petritsch Peter. Phytoestrogen tissue levels in benign prostatic hyperplasia and prostate cancer and their association with prostatic diseases. Urology. 2004 Okt; 64, 4: 707-11.
- Hong Sung Joon, Kim Sun Il, Kwon Soo Mee, Lee Jong Ran, Chung Bong Chul. Comparative study of concentration of isoflavones and lignans in plasma and prostatic tissues of normal control and benign prostatic hyperplasia. Yonsei Med J. 2002 Apr; 43, 2: 236-41.
- Berges R R, Windeler J, Trampisch H J, Senge T. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group.n Lancet. 1995 Jun; 345, 8964: 1529-32.
- Carbin B E, Larsson B, Lindahl O. Treatment of benign prostatic hyperplasia with phytosterols. Br J Urol. 1990 Dez; 66, 6: 639-41.
- Vahlensieck Winfried, Theurer Christoph, Pfitzer Edith, Patz Brigitte, Banik Norbert, Engelmann Udo. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int. 2015 Jun; 94, 3: 286-95.
- Hong Heeok, Kim Chun-Soo, Maeng Sungho. Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia. Nutr Res Pract. 2009 Okt; 3, 4: 323-7.
- Marks L S, Partin A W, Epstein J I, Tyler V E, Simon I, Macairan M L, Chan T L, Dorey F J, Garris J B, Veltri R W, Santos P B, Stonebrook K A, deKernion J B. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol. 2000 Mai; 163, 5: 1451-6.
- Leibbrand M, Siefer S, Schön C, Perrinjaquet-Moccetti T, Kompek A, Csernich A, Bucar F, Kreuter MH. Effects of an Oil-Free Hydroethanolic Pumpkin Seed Extract on Symptom Frequency and Severity in Men with Benign Prostatic Hyperplasia: A Pilot Study in Humans. J Med Food. 2019 Jun;22(6):551-559.
- Marks L S, Partin A W, Epstein J I, Tyler V E, Simon I, Macairan M L, Chan T L, Dorey F J, Garris J B, Veltri R W, Santos P B, Stonebrook K A, deKernion J B. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol. 2000 Mai; 163, 5: 1451-6.
- Katz Aaron, Efros Mitchell, Kaminetsky Jed, Herrlinger Kelli, Chirouzes Diana, Ceddia Michael. A green and black tea extract benefits urological health in men with lower urinary tract symptoms. Ther Adv Urol. 2014 Jun; 6, 3: 89-96.
- Pavone C, Abbadessa D, Tarantino M L, Oxenius I, Lagan? A, Lupo A, Rinella M. Associating Serenoa repens, Urtica dioica and Pinus pinaster. Safety and efficacy in the treatment of lower urinary tract symptoms. Prospective study on 320 patients. Urologia. 2010 Jan; 77, 1: 43-51.
- Vela-Navarrete R, Alcaraz A, Rodríguez-Antolín A, Miñana López B, Fernández-Gómez JM, Angulo JC, Castro Díaz D, Romero-Otero J, Brenes FJ, Carballido J, Molero García JM, Fernández-Pro Ledesma A, Cózar Olmos JM, Manasanch Dalmau J, Subirana Cachinero I, Herdman M, Ficarra V. Efficacy and safety of a hexanic extract of Serenoa repens (Permixon® ) for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH): systematic review and meta-analysis of randomised controlled trials and observational studies. BJU Int. 2018 Dec;122(6):1049-1065.
- Boyle P, Robertson C, Lowe F, Roehrborn C. Updated meta-analysis of clinical trials of Serenoa repens extract in the treatment of symptomatic benign prostatic hyperplasia. BJU Int. 2004 Apr;93(6):751-6.
- Wilt TJ, Ishani A, Rutks I, MacDonald R. Phytotherapy for benign prostatic hyperplasia. Public Health Nutr. 2000 Dec;3(4A):459-72.
- Hong H, Kim CS, Maeng S. Effects of pumpkin seed oil and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia. Nutr Res Pract. 2009 Winter;3(4):323-7.
- Lopatkin NA, Sivkov AV, Medvedev AA, Walter K, Schlefke S, Avdeĭchuk IuI, Golubev GV, Mel'nik KP, Elenberger NA, Engelman U. [Combined extract of Sabal palm and nettle in the treatment of patients with lower urinary tract symptoms in double blind, placebo-controlled trial]. Urologiia. 2006 Mar-Apr;(2):12, 14-9.
- Engelmann U, Walther C, Bondarenko B, Funk P, Schläfke S. Efficacy and safety of a combination of sabal and urtica extract in lower urinary tract symptoms. A randomized, double-blind study versus tamsulosin. Arzneimittelforschung. 2006;56(3):222-9.
- Wilt T, Ishani A, Mac Donald R, Rutks I, Stark G. Pygeum africanum for benign prostatic hyperplasia. Cochrane Database Syst Rev. 2002;1998(1):CD001044.
- Akbar Karami A, Sheikhsoleimani M, Reza Memarzadeh M, Haddadi E, Bakhshpour M, Mohammadi N, Mehdi Mirhashemi S. Urtica Dioica Root Extract on Clinical and Biochemical Parameters in Patients with Benign Prostatic Hyperplasia, Randomized Controlled Trial. Pak J Biol Sci. 2020 Jan;23(10):1338-1344.
- Ghorbanibirgani A, Khalili A, Zamani L. The efficacy of stinging nettle (urtica dioica) in patients with benign prostatic hyperplasia: a randomized double-blind study in 100 patients. Iran Red Crescent Med J. 2013 Jan;15(1):9-10. doi: 10.5812/ircmj.2386. Epub 2013 Jan 5.
- Safarinejad MR. Urtica dioica for treatment of benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled, crossover study. J Herb Pharmacother. 2005;5(4):1-11.
- Schneider T, Rübben H. Brennnesseltrockenextrakt (Bazoton-uno) in der Langzeittherapie des benignen Prostatasyndroms (BPS). Ergebnisse einer randomisierten, doppelblinden, placebokontrollierten Multicenterstudie über 12 Monate [Stinging nettle root extract (Bazoton-uno) in long term treatment of benign prostatic syndrome (BPS). Results of a randomized, double-blind, placebo controlled multicenter study after 12 months]. Urologe A. 2004 Mar;43(3):302-6. German.